Indications
Antibiotic Prophylaxis
Formulation
- 1 gram tablets are the most common
Regimen
Recommended Prophylaxis Regimens
Procedure Recommended Prophylaxis Penicillin / Cephalosporin Allergy Dental procedures Amoxicillin 2g orally (child: 50mg/kg up to 2g) 60 mins prior OR if oral not possible: Amoxicillin 2g IV (child: 50mg/kg up to 2g) Moderate risk allergy: Cefalexin 2g orally (child: 50mg/kg up to 2g) 60 mins prior OR if oral not possible: Cefazolin 2g IV (child: 30mg/kg up to 2g) Tonsillectomy / Adenoidectomy / All other procedures Amoxicillin 2g IV (child: 50mg/kg up to 2g) OR Vancomycin 1g IV infusion (1.5g for adults >80kg) (child: 30mg/kg up to 1.5g) High risk allergy: Clindamycin 600mg orally (child: 20mg/kg up to 600mg) 60-120 mins prior OR if oral not possible: Clindamycin 600mg IV infusion (child: 20mg/kg up to 600mg) Allergy and Clinical Notes:
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- Moderate risk penicillin allergy: History suggestive of moderate risk (e.g., delayed rash which is NOT urticarial or DRESS/SJS/TEN).
- High risk penicillin/cephalosporin allergy: History suggestive of high risk (e.g., anaphylaxis, angioedema, bronchospasm, urticaria, DRESS/SJS/TEN).
- Vancomycin-resistant enterococci: For patients colonised or infected, seek advice from Infectious Diseases (ID) for an appropriate regimen.
Prescription
Amoxicillin 1g capsules Qty 2 Directions : Take 2 capsules (2g) orally 60 minutes before dental procedures