Historical Development of CT[^18]

Sixth Generation CT: Helical (1990s)[^17]

  • Slip-ring technology: Developed to allow the gantry to rotate continuously without the restriction of wires.
  • Helical CT scanners: These systems acquire data while the table is moving.
  • Introduced helical scanning capabilities, improving speed and volume coverage.

Seventh Generation CT (Late 1990s – 2000)

  • Multiple Detector Array: Introduction of systems capable of capturing multiple slices simultaneously.

Tomographic Reconstruction[^19][^20]

  • An algorithm is used to produce the CT image, which serves as an attenuation coefficient map.
  • Filtered back projection is the most widely used reconstruction method in clinical CT scanners.
  • Bony pathology is very accurately seen with Multislice CT (MSCT).

Hounsfield Unit[^21]

  • The Hounsfield unit (HU) is a quantity commonly used in CT scanning to express CT numbers in a standardized and convenient form.
  • Hounsfield units, created by and named after Sir Godfrey Hounsfield, are obtained from a linear transformation of the measured attenuation coefficient.
  • This transformation is based on the arbitrary definitions of air and water.
  • Quantitative measurement of tissue density is possible, unlike in CBCT.

CT Numbers and Hounsfield Units for Various Substances[^22]

SubstanceHU
Air-1000
Lung-500
Fat-100 to -50
Water0
CSF15
Kidney30
Blood+30 to +45
Muscle+10 to +40
Grey matter+37 to +45
White matter+20 to +30
Liver+40 to +60
Soft Tissue, Contrast+100 to +300
Bone+700 (cancellous) to +3000 (dense)

Digital Image Display Window Level

Display Intensity Mapping

CT NumberDisplay Intensity
-1000 to P1Black
P1 to P2Gray (linearly)
P2 to +3000White

Calculation Formulas:

  • P1 = L – ½ W
  • P2 = L + ½ W

Example Settings:

  • W = 4095, L = 1048
  • W = 600, L = -100
  • W = 700, L = -650

Common Clinical Window Settings[^24]

  1. Bone Window

    • Center/Width (C/W): 1000, 2500
    • Range: +2250 HU to -250 HU
  2. Mediastinal Window

    • Center/Width (C/W): -50, 400
    • Range: +150 HU to -250 HU
  3. Lung Window

    • Center/Width (C/W): -600, 1700
    • Range: +250 HU to -1450 HU

Comparative Windowing Examples[^25]

  • Soft Tissue Focus: W:300, L:50
  • Bone/Dense Tissue Focus: W:3000, L:500

Contrast Agents[^26][^27]

  • Contrast agents frequently utilize Iodine.
  • These agents help to better visualize internal structures.
  • Tumors: Highly vascular tumors show enhancement, revealing the full extent and vascularity.
  • Differentiation: Helps differentiate tumors from cysts.
  • Speed: CT is the fastest imaging available, ideal for patients who are kyphotic, frail, or cannot stand still.