**DISCUSSION CASE** **Case description:** 62-year-old Female presents with the lesion shown. She noted the lesion three to four months ago. She remains mostly asymptomatic, although did give a history of occasional irritation of the site associated with the consumption of spicy / acidic foods. Her medical history is significant for hypercholesterolaemia and depression. She is a non-smoker and does not drink alcohol. **Activity:** 1. Identify the pathosis and describe the clinical features 2. What is the differential diagnosis? 3. What are the relevant clinical investigations? 4. What is the diagnosis? 5. How would you manage this patient?  #### Patient Profile and History A 62-year-old female presents for evaluation of a lesion first noticed three to four months ago. - **Symptoms:** Mostly asymptomatic, with occasional irritation at the site triggered by the consumption of spicy or acidic foods. - **Medical History:** Significant for hypercholesterolaemia and depression. - **Social History:** Non-smoker; does not consume alcohol. #### Case Activity 1. Identify the pathosis and describe the clinical features. 2. What is the differential diagnosis? 3. What are the relevant clinical investigations? 4. What is the diagnosis? 5. How would you manage this patient? Clinical intraoral photograph showing the upper right posterior gingiva. The image displays a distinct erythematous (red) lesion located on the attached gingiva adjacent to the premolars and molars. The surrounding mucosa appears relatively normal with visible stippling in some areas, while the affected area is smooth and inflamed. Several teeth are visible, including what appear to be dental restorations or crowns on the lower right quadrant. [^1]: Original PDF page 1: [[OPMD Case 2.pdf#page=1|OPMD Case 2, p.1]]