Mucoceles and ranulas

Mucoceles and ranulas are the same thing!

  • a ranula is termed a mucous retention cyst and occurs in the floor of mouth is mor elikley due to obstruction
  • a mucocele is termed a mucous extravasation cyst and occurs (usually in lower lip) in other salivary glands and is more likley due to trauma

Etiology and Pathophysiology

Mucoceles: often associated iwth a history of trauma, resulting in the leakage of fluid from the ducts or acini into the surrounding tissue Mucous retention cysts (Ranula): Typically caused by the obstruction of a duct rather than direct trauma

Contributory factors :

Trauma or obstruction

Prevalence

  • Very common
  • Especially in children and young adults due to higher rates of local trauma

Histological Features

Depends on if the lesion is intact or ruptured

  • intact lesions
    • Pseudocystic cavity containing mucus
    • Presence of numerous foamy epithelial histioctyes (muciphages), neutrophils and granulation tissue
    • No epithelial cystic lining; superficial oral mucosa may show variable atrophy in superficial mucoceles
  • **Ruptured Lesions **
    • Fragments of granulation tissue containing muciphages and neutrophils
    • Visible mucinous material
    • Associated salivary gland parenchyma may show obstructive changes, including acinar atrphy, ductal dilation with periductal hyalinization, interstitial lymphoplasmacytic infiltration and late-stage fibrosis

Clinical Features

Duration is variable and often dpeends on the level of inconvenience cause to the patient

Location

  • Mucocele: mucosa or vermillion of the lower lip though can occur at other intraoral sites
  • Ranula: floor of mouth

Appearance

  • Color ranges from deep blue to normal pink
  • commonly present as soft, painless swellings

Differential Diagnoses

  • Fibroepithelial polyp/ traumatic fibroma
  • Lipoma
  • Venous malformation

Ranula specific:

  • sialolithiasis
  • Sialadenitis
  • Vascular malformation

Relevant Clinical Investigations

  • Biopsy
  • Diascopy / blanching test
  • Aspiration
  • Ultrasound

Patient Management

Ranula:

  • removal of the lesion by complete excision without rupture, including removal of the associated minor salivary glands